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OOCYTE DONATION & EMBRYO DONATION (OD-ED)


Human Egg donation, first introduced in 1983, has evolved in a relatively short time into a common procedure that addresses a variety of reproductive problems. This method has provided key insights into the physiology and patho-physiology of reproduction and, like other ART, has engendered its share of controversy. The popularity of egg and embryo donation is evidenced by the rapidly increasing demand for services. In the USA, 10389 procedures involving fresh or frozen embyros procured through oocyte donation were reported to the CDC in 2000, nearly double from that reported in 1996. At our own centre, which performs close to 2400 ART cycles per year, almost 1000 were those of oocyte and embryo donation. This increase is largely due to the rising percentage of women who remain childless past the age of 37, a number that has increased sharply over the past 20 years. Many women are marrying later, or are pursuing education and vocation and deliberately delaying childbearing. This section will highlight the various indications for oocyte donation, recruitment of oocyte donors, preparation of the recipient, success rates and obstetrical outcome of these pregnancies. Egg sharing between one professional egg donor and several recipients is a novel way of reducing the cost of treatment. The next frontier in oocyte donation may include use of enucleated donor oocytes which would allow recipients to use their own genetic material. Improvements in oocyte freezing may soon permit "egg banks" to be set up, reducing the need to synchronize patients while allowing for quarantine.

WHO NEEDS EGG DONATION??
1. Patients with repeated IVF failures owing to poor egg quality / vacuolated eggs/eggs with thick or dark zona, embryos with moderate to severe fragmentation (these are terms which might have been used in the discharge summary of your previous IVF cycles)
2. Patients above the age of 37 with decreased ovarian / egg reserve
3. Patients with decreased ovarian / egg reserve at any age indicated by low serum AMH levels, elevated serum FSH levels or decreased antral follicle counts on ultrasound
4. Patients with premature menopause
5. Patients with premature ovarian failure
6. Patients whose one or both ovaries have been removed with poor ovarian stimulation with FSH injections

SELECTION OF EGG DONORS
Fortunately, most ART banks have a large pool of young, healthy, fertile egg donors from all backgrounds and all walks of life. There are options to select from Indian, African, Caucasian, Georgian, Russian, Turkish, Chinese, Asian, South east asian and so on as per your requirements Egg donors are screened as per international standards .

Egg donors are screened as per international standards

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