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Gamete Intrafallopian Transfer (GIFT), developed in 1984. 

 

This is a treatment of choice in unexplained infertility and patients having cervical factors and immunological factors. In this procedure mixture of sperm and eggs is placed directly into one of the woman’s fallopian tubes during a laparoscopy. Conception occurs in the fallopian tube. Once fertilized, the embryo then travels into the uterus, just as in a natural cycle.
As with other ART procedures, GIFT requires that the woman’s ovaries first be stimulated with hormonal medication to encourage the development of multiple oocytes. This enhances the possibility of fertilization. With GIFT, fertilization takes place inside the woman’s body. However, GIFT can only be used in patients with healthy fallopian tubes ( atleast one).

Zygote Intrafallopian Transfer (ZIFT) combines aspects of both IVF and GIFT. Protocols for ovarian stimulation are similar to those used for IVF and GIFT. Eggs are collected and fertilized by the partner’s sperm in the laboratory. What makes ZIFT different from IVF is that the embryo is placed into the woman’s fallopian tube via laparoscopy instead of the uterus.

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